Junta de Andalucía UMA

Eligible Research Areas

As it is explained in Section How to apply, to participate in the selection process applicants must submit a proposal by filling in an online application form and uploading the required documents. Applicants must use official templates for Curriculum Vitae and Expression of Interest, which can be downloaded in Word format and must be uploaded in PDF format in the specific section of the application form.

In the document “Expression of Interest”, applicants must indicate a Research Area and prioritise, in order of interest, all the thesis research fields offered by BIONAND research groups in that area, as listed on the NanoMedPhD webpage.. There will be a specific ranking list for each Research Area.

Thus, for a submitted proposal to become an Eligible Proposal it must also meet the following eligibility criteria: the proposal needs to be related to one of the three eligible Research Areas of the Programme to be selected in the on-line application form (Nanodiagnostics, Therapeutics Nanosystems and Regenerative Nanomedicine).

Below the three NanoMedPhD Research Areas are detailed (click [+] to expand the description of each area):

This area is focused around the implementation of more efficient diagnostic and prognosis devices, both in vivo and in vitro, with the objective of optimizing the identification of diseases or predisposition to them, as well as it’s progression at a cellular or molecular level by using nanodevices.

The general research lines within this area are:

  • Development of devices and sensors based on nanotechnology for the detection and reliable measurement of the presence or concentration of one or more specific biomarkers and biomolecular interactions by measuring changes in response to thermal, electronic, magnetic, chemical or other stimuli.
  • Develop nanomaterials as nanometric markers and contrast agents for improved image-based diagnostic approaches.
  • The identification, evaluation and validation of new pathology-specific biomarkers.

This area will focus on the development and research of nanosystems which protect, transport and release drugs or therapeutic agents by a controlled method leading to an easier administration, being more selective and effective, and therefore less toxic.

The general research lines within this area are:

  • Study and develop combinations of new agents (enzymes, proteins, nucleic acids) and nanostructures with therapeutic properties.
  • Develop nanosystems that improve pharmokinetic, pharmodynamic and controlled release of therapeutic agents.
  • Identify nanosystem-based transfection methods for gene therapy.
  • Development of monitored treatments that combine therapeutic and imaging aspects, thus allowing the administration or effect of a treatment to be more easily followed by in vivo imaging (theranostics).

This area deals with the repair or replacement of diseased or damaged tissues and organs by applying methods from gene therapy, cell therapy, the dosage of bioactive molecules and tissue engineering, by stimulating repair mechanisms of the own body. The production of new materials and support systems, the use of stem cells (adult, embryonic and iPS) and the production of molecules and biomimetic peptides which serve as signals for cell adhesion and differentiation are the main focuses of this area.

The general research lines within this area are:

  • Molecular and cellular functionalisation of biomaterials for the creation of tissue engineering products.
  • Biocompatibility and toxicity of implantable devices.
  • Cellular and molecular mechanisms implicated in the regeneration of organs and tissues.

The research activity (thesis projects) developed in these scientific areas within the framework of the NanoMedPhD Program will be developed in the Andalusian Centre for Nanomedicine and Biotechnology (BIONAND, www.bionand.es), a mixed research centre conceived as a space for research excellence in nanomedicine, being the first specialized centre in Spain focused exclusively towards healthcare-applied nanotechnology research with the aim of creating a world-class centre of excellence.

The research groups located in BIONAND have a wide expertise in nanomedicine, and deal with the most important clinical challenges considered for Nanomedicine in Horizon 2020, such as inflammation, neurodegenerative diseases, cardiovascular and cancer. Researchers participating in the NanoMedPhD program will become a member of a BIONAND research group and will receive scientific supervision from Principal Investigators of the assigned group. Principal Investigators of BIONAND and their research lines and expertise are shown in section Research at Bionand à Thesis Research fields and Principal Investigators.

Política de cookies En esta web utilizamos cookies para darte una mejor navegación. Si continúas navegando consideramos que aceptas su uso. Más información aquí. Continuar